ea0094op2.2 | Metabolism, Obesity and Diabetes | SFEBES2023
Srnic Nikola
, Dearlove David
, Jonhson Elspeth
, O'Rourke Paige
, Parry Sion
, Hodson Leanne
Background: Intrahepatic triglyceride (IHTG) accumulation, a cardiometabolic disease risk factor, is greater in individuals consuming saturated-fat (SFA) compared to polyunsaturated-fat (PUFA) enriched diets. We have demonstrated that compared to SFA, PUFA are preferentially partitioned into oxidation pathways, which may, in part, explain the divergence in IHTG accumulation. However, it remains unclear if this preferential handling is maintained when hepatocel...